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CORTI OFF+ is the natural help for cortisol control. Based on Vitacholine, L-theanine, soy phospholipids, vitamin B6 and Ashwagandha, it manages to keep your blood sugar stable, increase cognitive function, improve sleep and reduce cortisol.

Also known as the stress hormone because its production increases as a result of psycho-physical stress, cortisol promotes protein catabolism, decreases the synthesis of collagen and reduces the strength of the immune system. Such conditions are not particularly pleasant for those who practice physical activity.

CORTI OFF+ is the natural answer in order to maintain low cortisol levels and fight stress.

Dry extract of KSM-66® Ashwagandha isone of them. 


Ashwagandha comes from ayurvedic medicine, the traditional system of medicine from India. Known from centuries as an adaptogenic herb that helps the body successfully adapt to stressful conditions. The roots are the main portion of the plant that are used therapeutically. KSM-66® Ashwagandha has been created via a process that took 14 year. It is the highest-concentration extract on the world market today that is drawn using only the roots of the ashwagandha plant. It is produced using the first-of-its-kind extraction process, based on ‘’Green-Chemistry’’ principles, without using alcohol or any other chemical solvents. KSM-66® Ashwagandha has been clinically proven to: help reduce stress, anxiety, cortisol levels and stress-related food cravings; help promote enhanced memory and cognitive function; help promote endurance, strength, muscle size and muscle recovery rate; help maintain peak sexual performance health in both men and women, and testosterone in men. KSM-66® Ashwagandha is the highest concentration full-spectrum root extract available on the market. A ‘full-spectrum’ extract is an extract which maintains the balance of the various constituents as in the original herb, without over-representing any one constituent. The ashwagandha herb’s efficacy derives from a complex blend of active constituents, mainly alkaloids like whitanine, somniferine, tropine and steroidal lactones called whitanolides. All these constituents need to be present in their natural proportions, and hence it is important for an extract to be full-spectrum. Only KSM-66® Ashwagandha is standardized to the highest percentage of whitanolides on the market today, >5% by HPLC, derived only from the roots of the plant. KSM-66® Ashwagandha is supported by several clinical trials. One of them, published in the Indian Journal of Psychological Medicine showed that KSM-66® Ashwagandha achieved a highly significant reduction in stress and anxiety, and serum cortisol level (28% reduction).


Ashwagandha is supported by another active principle able to control cortisol: L-teanine. This substance modulates the brain waves to ensure better mental and physical performance during a stressful situation.

Among the best-known soy phospholipids is phosphatidylserine which features remarkable qualities at the cognitive level. This phospholipid is deemed to be able to reduce cortisol in the blood up to 20%. It also allows more effective communication between neurons, facilitating the conduction of nerve impulses, resulting in a neuro-muscular system more effective. Several studies confirm its power to increase the memory skills and induce a state of relaxation and calm. It shares such actions with the choline, found in CORTI OFF + is Balchem’s VitaCholine®. VitaCholine® is the premier source of choline, made to the highest standards in order to deliver relevant and compelling health benefits. Considered as the global leader in choline, VitaCholine® has long been acknowledged as the quality choice for use in dietary supplements. Choline is an essential dietary nutrient. It supports cardiovascular health, the normal liver function and fat metabolism, it facilitates healthy metabolism and it helps the brain send faster messages throughout the nervous system. VitaCholine® is a verified Non-GMO project and is the first and only choline to attain USP Verified Dietary Ingredient status.  It also meets several important industry standards such as the most current USP (United States Pharmacopeia) monograph, the most current FCC (Food Chemicals Codex) monograph, it’s kosher and halal and it meets California Prop 65 requirements .Choline is involved in the synthesis of the neurotransmitter acetylcholine, which is needed for the proper function of the parasympathetic nervous system. Acetylcholine is also involved in other essential processes such as: slowing down the heart rate, the stimulation of salivary gland secretion as well as the stimulation of gastric and pancreatic secretions. This neurotransmitter also supports intestinal peristalsis as well as all the general digestive functions. Choline is also vital for the integrity and fluidity of cell membranes because it functions as a precursor of the phospholipid phosphatidylcholine. Choline and Betaine together also contribute to normal cardiovascular function, counteracting the effects of homocysteine, which is associated with increased risk of cardiovascular problems such as atherosclerosis. Choline maintains normal liver function through the role it plays in fat metabolism. The liver produces VLDL, very low density lipoproteins, as a way to export fats out of the liver for storage or to muscles for immediate conversion into energy. VLDLs are composed of an inner core of lipids and an outer layer of phospholipids. As a precursor of the phospholipid phosphatidylcholine, free choline is a required raw material to make VLDL. Without adequate levels of free choline, transport slows and fats will begin to build up within the liver. According to several studies, choline also has the ability to prevent damage to the liver (hepatoprotective properties) that can be caused by hepatotoxic (damaging to liver cells) drugs as well as anti-inflammatory and cardioprotective drugs. An adequate choline intake will lead to a reduction in inflammatory marker concentrations and inflammatory cytokines concentrations, both of which are involved in the inflammation process.

Finally, CORTI OFF + contains vitamin B6 that is involved in the synthesis reactions of many neurotransmitters including serotonin, known for its positive effects on mood. It also plays a role in the metabolism of tryptophan, the precursor of serotonin and melatonin, which regulates the sleep-wake cycle.


How to use
Take 2 caps once a day.
Ingredients - Nutritional Info

Choline bitartrate, L-Teanine, Gelatin (capsule), KSM-66®* Ashwagandha Root Extract [Ashwagandha (Withania somnifera (L.) Dunal) root d.e. stand. 5% withanolides (contains milk)], Bulking agent: microcrystalline cellulose), Soy phospholipids powder (of which 70 % phosphatidylserine), Anti-caking agents: magnesium salts of fatty acids, silicon dioxide; Colour: silicon dioxide; Vitamin B6 (pyridoxine hydrochloride).

*KSM-66 is a registered trademark of Ixoreal Biomed Inc

Additional Information

For serving 2 cps
KSM-66® Ashwagandha radice e.s. 150 mg
VitaCholine® (choline bitartrate) 200 mg
L-Teanine 200 mg
Soy phospholipids powder (of which 70 % phosphatidylserine) 70 mg
Vitamin B6 0.42 mg
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Available Product code CORTI-OFF


CORTI OFF+ is the natural help for cortisol control. Based on Vitacholine, L-theanine, soy phospholipids, vitamin B6 and Ashwagandha, it manages to keep your blood sugar stable, increase cognitive function, improve sleep and reduce cortisol.
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