PREBIO+ is a water-soluble food supplement in powder, based on a prebiotic mix of fructooligosaccharides (FOS), inulin and gluco-oligosaccharides (GOS), and enriched with nucleotides and tyndallized probiotic bacteria. The prebiotic supplement PREBIO+ promotes the balance of the intestinal flora, known as eubiosis.


The intestinal bacterial flora, or human intestinal microbiota, is represented by a thriving community of bacteria residing in the gastro-intestinal tract, which communicate with the body and interact with its physiological functions. The most common eubotic bacterial species are lactobacilli and bifidobacterial. In addition to the bacterial flora, our intestine also contains other microorganisms - potentially pathogenic - such as viruses and fungi. In conditions of balance (or eubosis), these organisms do not exert any harmful effect. The balance of the intestinal bacterial flora plays a key role in regulating the immune function, ensures the integrity of the intestinal muscosa and enhances its barrier effect, promotes digestive processes and contributes to emotional and behavioural responses. The state of eubiosis, however, may be affected by changes in lifestyle or eating habits, psychophysical stress, intense sports activity, the effects of antibiotic therapies or the attack of pathogens and its imbalance is related to many immune-inflammatory disorders. It is well known that the diet can modulate the quality of the intestinal microbiota, because it provides the nutrients necessary for the growth of different species of microorganisms. It is therefore essential to ensure the correct supply of nutrients and, when necessary, to intervene with a prebiotic supplement capable of promoting the eubosis and variety of the microbiota.

PREBIO+ is a supplement based on prebiotics, nucleotides and tyndallized bacteria, intended to stimulate the growth of eubiotic bacteria and to help restore its precious balance. Even in those who practice intense sports, physical stress from training may require supplementation with a prebiotic.

The prebiotic supplement PREBIO+ contains prebiotics, i.e. non-viable and non-digestible organic substances, mainly water-soluble fibres: inulin, FOS and GOS under the Bioecolians® brand. These substances can promote the growth of one or more bacterial species useful for the development and maintenance of the balance of the intestinal flora. In fact, the prebiotics of PREBIO+ are fermented by numerous bacterial species: their fermentation gives rise to some molecules, lactic acid and short-chain carboxylic acids, which create environmental conditions hostile to the development of pathogenic organisms and favourable to the growth of bifidobacteria and lactobacilli. In addition to protecting the biodiversity of the intestinal microbiota, PREBIO+ prebiotics help to regulate intestinal transit, inducing an increase in faecal mass and in the number of evacuations.

The activity of PREBIO+ is also supported by the mixture of Ribocare® nucleotides. Nucleotides are essential components of nucleic acids (RNA and DNA) and participate in a large number of biochemical processes in the body. However, many cells with high turnover rates, such as those in the gastrointestinal tract, cannot always synthesize enough of them. Integration with nucleotides has been shown to have several positive effects on intestinal function, immune response and composition of the intestinal bacterial flora.

Finally, the formulation of the prebiotic supplement PREBIO+ contains a blend of tyndallized probiotics, also known as para-probiotics. Para-probiotics are bacteria that have undergone a special "inactivation" heat treatment. This process makes the bacterial cells unable to metabolize and reproduce: their activity is therefore not linked to the ability to multiply, or to colonize a specific physiological site. The beneficial properties of tyndallized bacteria are due to the action of their fragments and the products of their metabolism, which are obtained through the heat treatment they undergo. These substances help to create an environment suitable for the recolonization of eubiotic species, have an immunostimulant activity and counteract the growth of pathogenic species.

PREBIO+ is the complete prebiotic supplement that helps to modulate the immune response, regulates the intestinal transit and optimizes the activity of the digestive system because it promotes the balance of the intestinal microbiota.

Add 1 sachet (5 g) in a glass of water, mix carefully and take once a day.
Ingredients - Nutritional information

Fructo-oligosaccharides (FOS), Inulin, α-Gluco-oligosaccharide (GOS) (Bioecolians®), Tyndallized* bacteria blend (L. casei HA-108, L. acidophilus HA-122, L. plantarum HA-119, S. thermophilus HA-110) (contains milk), Nucleotides 5’-monophosphate (Ribocare®, Anti-caking agent: silicon dioxide.

*No viable cells

Media Analysis
For serving 5 g
FOS 3 g
Inulin 1.3 g
GOS (Bioecolians®) 0.5 g
Nucleotides (RIBOCARE®) 25 mg
Tyndallized bacteria 25 mg
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Food needs
Gluten Free
Raw Material
Bioecolians Ribocare