REM+ is a plant complex with vitamin B6, Tryptophan and Melatonin, with calming, relaxing and sleep-inducing properties, able to regulate the sleep-wake cycle.

REM + consists of California poppy, Protopine, Red poppy, Valerian, Vitamin B6, L-Tryptophan and Melatonin.

The plant complex (California poppy, Red poppy and Valerian), as such, enhances the final effect of each single component, and has a sedative, calming, relaxing and anti-spasm effect. In particular the California poppy is indicated for the treatment of insomnia with nocturnal awakenings, for the maintenance of a good quality sleep.

The Protopine, an alkaloid of the California poppy, and the Valerian are powerful sleep-inducing substances. The latter has anti-anxiety, sedative and calming effects, and is indicated for the treatment of mild anxiety, irritability, insomnia, headache, gastric spasms and palpitations.

Vitamin B6 and the Tryptophan, an essential amino acid, are essential for the synthesis of Serotonin, a neurotransmitter, also known as 'feel good hormone’, which is the precursor of Melatonin. Melatonin is the hormone that regulates the body's circadian cycle, that is the sleep-wake cycle. Its secretion is regulated by light. When the stimulus arrives at the retina, a signal is transmitted to the epiphysis where its secretion is inhibited. On the contrary, the darkness stimulates the Melatonin release.



Take 1-2 capsules per day with water or another beverage, 30 minutes before bedtime in the evening.


Golden poppy (Escholtzia californica Cham.) aerial parts d.e. stand. 0,2% total alkaloids expressed as protopine, L-Trypthophan, Capsule: edible gelatin; Red Poppy (Papaver rhoeas L.) flowers d.e., Valerian (Valeriana officinalis L.) root d.e. stand. 0,8% total sesquiterpenic acids expressed as valerenic acid, Bulking agent: microcrystalline cellulose; Pyridoxine hydrochloride (vitamin B6), Anti-caking agents: magnesium salts of fatty acids, silicon dioxide; Melatonin.

Training Day

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Normal Day

  • morning
  • lunch
  • afternoon
  • dinner
  • night


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Analisi media

For serving 2 cps
Vitamin B6 2.1 mg (150% RDA)
Escolzia dry extract 380 mg
Intake of protopin 0.76 mg
Red Poppy dry extract 180 mg
Valerian dry extract 160 mg
Intake of valerenic acids 1.28 mg
L-tryptophan 200 mg
Melatonin 1 mg

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